Describes By : Dr. Robert Rowen


 


 
 

 

Bali has first human bird flu death

JAKARTA, Indonesia (Reuters)—An Indonesian woman has died of bird flu in Bali, the first human death from the virus on the resort island hugely popular with foreign tourists. A health-ministry official said on Monday the 29-year-old woman came from west Bali. She died on Sunday in hospital after suffering from high fever. Her five-year-old daughter also died recently after playing with chickens, but it was unclear if the girl died of bird flu.

Joko Suyono of the ministry’s bird flu center said a 2-year-old girl living close by had also developed bird flu symptoms, but was recovering in hospital. Test results had not come back yet. News of the woman’s death will be a blow to Bali, which is the center of Indonesia’s tourism industry and has been trying to shake off the impact of several deadly bomb attacks by Islamic militants in recent years.

The woman from a village in the district of Jembrana was suffering from a high fever before dying of multiple organ failure, said Ken Wirasandi, a doctor at the Sanglah hospital in the Balinese capital Denpasar. Suyono said by telephone a second laboratory test had confirmed the woman had the H5N1 bird flu virus. Suyono said there had been sick chickens around the woman’s house, and many had died suddenly in recent weeks.

“The villagers didn’t burn the carcasses. Instead they buried them or fed them to pigs,” Suyono added.Contact with sick fowl is the most common way for humans to contract the H5N1 virus. The woman had started showing symptoms more than a week ago, but was only admitted to hospital six days later. She was transferred to a bigger hospital in Denpasar on Friday, where she was treated in the isolation unit, Suyono said. Don’t Miss

He said initial investigations indicated last month the daughter had become sick after playing with chickens and died a week later. “We were unable to retrieve any tissue samples, so we can’t confirm whether she died of bird flu,” Suyono added.

Bird flu story source: CNN online
 

H5N2 bird flu virus detected in Italian poultry

Italy - (Promed) - An outbreak of low pathogenic avian influenza, type H5N2, has been diagnosed on a poultry farm in Lugo, Italy. This has been notified by the Ministry of Agrculture.

Lugo is 25 km(15.5 miles) west of Ravenna, in Emilia Romano. The farm included 7000 adult ducks, 3000 geese and 150 chickens. The infection was detected within the framework of the annual, routine sero-surveillance activities. No clinical symptoms were seen.

The holding was confined, and the animals will be culled. A restriction zone of one-km(.6 mile) radius has been imposed around the site. Last week, an infected hobby-holding was found.

Bird flu story source: Promed

Italy minister says Russian ban on poultry unjustified

ROME, August 21 (RIA Novosti) - Italian Agriculture Minister Paolo De Castro said Russia’s ban on poultry imports from Italy was ungrounded, a local business daily reported Tuesday.

The Russian agricultural regulator introduced Monday a temporary ban on Italian poultry imports to Russia. The ban covers Italian imports of live poultry, eggs and all poultry products, as well as used equipment for keeping, slaughtering and processing poultry.

“Our poultry control is one of the strictest in Europe, and poultry deliveries to the domestic and foreign markets come exclusively from healthy birds,” the Il Sole-24 ore newspaper quoted the minister as saying.

The daily said that although two outbreaks of the H5N2 virus, which is harmless to humans, had been detected in Italy, the country maintained bird flu under control.

Bird flu story source: Novosti
 

Bird Flu in Chickens, Ducks Spread to Two More Vietnam Provinces

Authorities in Vietnam confirmed Saturday that bird flu has spread to two more provinces in the country.

That brings the total to four of Vietnam’s 64 provinces where the H5N1 virus has been found in recent outbreaks.

Agriculture officials say the virus killed 250 young chickens in the southern Dong Thap province about a week ago. They report another 150 ducks and 35 chickens were sick with the virus on Wednesday in the northern Thai Nguyen province.

The virus had earlier been reported in the northern provinces of Dien Bien and Cao Bang.

Bird flu story source: VOA


Deadly bird flu found in German poultry farm

BERLIN (Reuters) - An outbreak of deadly bird flu has been identified in a southern German poultry farm, a spokeswoman for Bavaria’s environment ministry said on Saturday.

The spokeswoman said dead ducks from the farm in Wachenroth in Bavaria’s Erlangen-Hoechstadt area had tested positive for the highly pathogenic H5N1 strain of the virus, which can be lethal for people living in close contact with birds.

All 160,000 birds in the farm would be culled, the ministry spokeswoman said. The farm has been sealed off.

Local authorities had earlier said the farm contained some 44,000 birds. Officials discovered the infection after more than 400 ducks at the farm died over a short period of time.

Germany identified several cases of the deadly H5N1 strain in wild birds in Bavaria in June. A string of bird flu infections were also registered in Germany last year.

Earlier this week, Russia banned poultry imports from Italy to prevent the spread of bird flu after outbreaks there.

Source of bird flu story: Reuters


Government Watchdog Reports Bird Flu Outbreak in Krasnodar ( Russia )

A government watchdog on Tuesday reported the third outbreak this year of the deadly H5N1 strain of bird flu after 410 birds died on a poultry farm in the Krasnodar region, but the growing poultry sector is set to withstand the scare.

Another 414 birds were culled and strict quarantine measures were put in place at the farm in the Black Sea region after local laboratory tests confirmed the presence of the virus in dead birds, the Agriculture Ministry’s Federal Service for Veterinarian and Vegetation Sanitary Supervision said.

“It’s serious enough to bring in strict measures, including quarantine, to make sure it does not spread,” watchdog spokesman Alexei Alexeyenko said. “An investigation is being carried out to determine the source of the infection.” The highly pathogenic H5N1 strain was responsible for the deaths of birds at the Lebyazhye-Chepiginskoye farm, in the same region where the virus was detected in dead domestic birds in January.

The second outbreak this year occurred in February, when several cases in towns around Moscow were traced to the city’s best-known pet market. The country expects to boost poultry meat output 16 percent this year to about 1.8 million tons, cutting the share of imports in domestic consumption. Domestic poultry producers last year supplied about 53 percent of the country’s consumption.

Dmitry Rylko, general director of the Institute for Agricultural Market Studies, said the size of the country and its quick reaction to bird flu cases offered commercial poultry farmers protection against bird flu. “Such cases will be repeated from time to time in various regions of the world, including Russia,” he said.

“In Russia, large-scale commercial farming is quite well protected against it due to good quarantine measures and the very low density of the poultry population, even in the south.”

Bird flu story source: Moscow Times


Indonesia reports 85th bird flu death

JAKARTA (AFP) — A 33-year-old Indonesian man from Sumatra island died of bird flu on Thursday, bringing the death toll in the world’s worst-affected nation to 85 and the global toll to 200, health officials said.

The plantation worker died at 2:00 pm (0700 GMT), the doctor treating him at the state general hospital in the city of Pekanbaru, Azizman Daad, told AFP. A health ministry official earlier confirmed that the man was infected with the deadly H5N1 virus, after two tests came back positive.

The archipelago nation has now reported 106 cases overall, including the 85 deaths. Daad said it was not clear whether the man had come into contact with infected poultry, but he had bought two live chickens at a local market.

The patient was taken to hospital in Pekanbaru on Saturday and transferred on Monday to the general state hospital, the facility designated by the government to treat bird flu patients in the region.Separately, two children and an adult on the island of Bali were being treated as suspected carriers of the virus, said Putu Andrika, from the bird flu team at Sanglah general hospital in the capital Denpasar.

“They are not in critical condition,” Andrika said. Tests were being carried out to confirm whether they were infected, he added.

Bird flu story source: AFP

 

Deadly New Virus Draws Experts to "Hot Zones"

Bijal P. Trivedi
National Geographic Today
January 21, 2003

This summer, a team of virus hunters will journey to Australia, Malaysia, India, Sumatra and Thailand to explore what they call "hot zones"—sites where deadly new diseases have emerged.

In all the locations the common enemy is the Nipah virus, or a relative. The Nipah broke out in Malaysia in 1998. Now known to be transmitted by a fruit bat, it first killed thousands of pigs. Within weeks, it spread to people. The final human death toll was more than 110.

Now the virus hunters are on the move to learn why and how the Nipah virus strikes. Their research can help head off not only the Nipah but also other virulent diseases that break out suddenly to plague man and beast.

To curtail the initial Nipah outbreak, the Malaysian government slaughtered 1 million pigs—decimating the local swine industry.

"We want to know what changes drove this virus to emerge in the first place," says Peter Daszak, executive director of the Consortium for Conservation Medicine, a research group that focuses on emerging diseases, based at Wildlife Trust in Palisades, New York. "What conditions allowed this virus to jump from bats to pigs to people?"

The summer's investigations take on a new urgency because of recent reports that the Nipah virus, and other similar ones, may be more widespread in Southeast Asia than anybody recognized.

A Quick Killer

The National Institute of Health has awarded $1.4 million to the Consortium to fund further research on the Nipah virus and the related Hendra virus, also carried by fruit bats.

Fruit bats range from Southeast Asia all the way to Africa, raising concerns that different species may harbor more dangerous variants of the Nipah. "There are probably related viruses all over the area with the potential not just to cause outbreaks in agricultural stock but also to cause serious disease in humans," says Stephen Morse, a viral epidemiologist at Columbia University in New York, director of Columbia's Center for Public Health Preparedness and author of the book "Emerging Viruses."

In Malaysia, Nipah's host, or "reservoir," is a large fruit bat, Pteropus vampyrus, with a body the size of a small puppy and a 5-foot wingspan.

Hume Field, a wildlife veterinarian at the Queensland Department of Primary Industries, in Brisbane, Australia, who was in Malaysia in 1999 during the outbreak, helped determine that local fruit bats carried the disease.

Field and another colleague netted more than 300 bats and sent blood samples to labs in Australia—they tested positive.
 

Half the victims will die if flu virus mutates: Expert

Published on: Wednesday, October 19, 2005

PETALING JAYA: The scenario if the deadly H5N1 virus mutates into a strain that can be transmitted from person to person is that half those infected could die. "This is because we don't have natural immunity to fight back," said Asia Pacific Society for Medical Virology president Prof Emeritus Datuk Dr Lam Sai Kit (pic).

He said as many as 20 per cent of the world's population could contract the flu. Many would not survive. "One has to look at the facts. There have been more than 100 cases and over half of them have died.

"When there is human-to-human infection, the scenario could be pretty horrible even if the virus does not change in virulence. Hopefully, the mortality rate will be lower. "There is no telling when this will happen. We have to take advantage of this window of opportunity and be prepared," said Dr Lam, who headed the team that discovered the Nipah virus.

The World Health Organisation warned last month that bird flu could mutate into a form that could be passed between humans, and that the world was on the brink of a pandemic. Dr Lam believes that "self-discipline and self-quarantine" must be practised to reduce exposure in the event of such a crisis.

He said the authorities should provide guidelines for home nursing and prevention among family members, and advise the people when to take a patient to hospital to avoid taxing health facilities.

By then, health services would be overwhelmed and no country would be able to provide enough hospital beds, he said. At the same time, he said, essential services such as electricity, water, transport and food supply, should be maintained.

In the meantime, surveillance for respiratory diseases must be stepped up, and any increase of flu-like cases must be investigated, he said.
 

OUTBREAK NEWS: NIPAH VIRUS

Nipah virus is a newly recognized zoonotic virus. The virus was discovered in 1999. It has caused disease both in animals and in humans, through contact with infectious animals. The virus is named after the location where it was first detected in Malaysia. Nipah is closely related to another newly recognized zoonotic virus (1994), called Hendra virus, named after the town where it first appeared in Australia. Both Nipah and Hendra are members of the virus family Paramyxoviridae. Although members of this group of viruses have only caused a few focal outbreaks, the biologic property of these viruses to infect a wide range of hosts and to produce a disease causing significant mortality in humans has made this emerging viral infection a public heath concern.

Natural host

It is currently believed that certain species of fruit bats are the natural hosts of both Nipah and Hendra viruses. They are distributed across an area encompassing northern, eastern and south-eastern areas of Australia, Indonesia, Malaysia, the Philippines and some of the Pacific Islands. The bats appear to be susceptible to infection with these viruses, but do not themselves become ill. It is not known how the virus is transmitted from bats to animals.

Transmission

The mode of transmission from animal to animal, and from animal to human is uncertain, but appears to require close contact with contaminated tissue or body fluids from infected animals. Nipah antibodies have been detected in pigs, other domestic and wild animals. The role of species other than pigs in transmitting infection to other animals has not yet been determined.

It is unlikely that Nipah virus is easily transmitted to man although previous outbreak reports suggest that Nipah virus is transmitted from animals to humans more readily than Hendra virus. Despite frequent contact between fruit bats and humans there is no serological evidence of human infection among bat carers. Pigs were the apparent source of infection among most human cases in the Malaysian outbreak of Nipah, but other sources, such as infected dogs and cats, cannot be excluded. Human-to-human transmission of Nipah virus has not been reported.

Clinical features

The incubation period is between 4 and 18 days. In many cases, the infection is mild or inapparent (sub-clinical). In symptomatic cases, the onset is usually with influenza like symptoms, with high fever and muscle pains (myalgia). The disease may progress to inflammation of the brain (encephalitis) with drowsiness, disorientation, convulsions and coma. Fifty percent of clinically apparent cases die.
 

Treatment

No drug therapies have yet been proven to be effective in treating Nipah infection. Treatment relies on providing intensive supportive care. There is some evidence that early treatment with the antiviral drug, ribavirin, can reduce both the duration of feverish illness and the severity of disease. However, the efficacy of this treatment in curing disease or improving survival is still uncertain.

Protection of health care professionals

The risk of transmission of Nipah virus from sick animals to humans is thought to be low, and transmission from person-to- person has not yet been documented, even in the context of a large outbreak. Therefore, the risk of transmission of Nipah virus to health care workers is thought to be low. However, transmission without percutaneous exposure (through a break in the skin barrier) is theoretically possible, as respiratory secretions contain the virus. This is why it has been categorized as a biohazardous agent that should be managed in a high-level biosecurity laboratory. It is recommended that close contact with body fluids and infected tissues be avoided if Nipah infection is suspected.
 

Outbreaks of Nipah and Hendra viruses

From September 1998 to April 1999, there was a large outbreak of encephalitis in Malaysia. During the investigation of this outbreak, Nipah virus, a previously unrecognized virus, was identified as the causal agent. A total of 265 people were infected, of whom 105 died. Ninety-three percent of cases had occupational exposure to pigs. An associated outbreak among abattoir workers in Singapore during March 1999 led to 11 cases, with one death. These workers had been handling pigs that had been imported from the outbreak areas in Malaysia.

There have been three recognized outbreaks of Hendra virus in Australia in 1994 and 1999. Three human cases, leading to two deaths, were recorded in the 1994 and 1995 outbreaks. In 1995 a horse was infected, with associated human cases. The precise mode of virus transmission to the three Australian patients is not fully understood. All three individuals appear to have acquired their infection as a result of close contact with horses which were ill and later died.

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